Obstructive sleep apnoea with co existent Kleine-Levine syndrome in a middle-aged man

Kleine-Levine Syndrome Co-occuring with Bipolar Disorder.

Klein-Levine syndrome (KLS) is a rare syndrome (1-2 reported cases per 1 million) that affects mostly men in young adulthood (1,2). The etiology of KLS is unknown however the reported flu-like symptoms prior to the initial KLS attack suggest that autoimmune mechanisms and genetic factors might have a role in the ethiopathogenesis (3). The KLS attacks are characterized by hypersomnia (15-21 hour...

Insulin Sensitivity and Insulin Resistance in Non-Diabetic Middle-Aged Patients with Obstructive Sleep Apnoea Syndrome

Background Obstructive sleep apnoea syndrome (OSAS) has been linked with abnormal glucose metabolism, insulin resistance (IR) and development of diabetes mellitus. Methods Non-diabetic patients (n=69) with OSAS, diagnosed by polysomnography, were prospectively recruited. To evaluate IR among OSAS patients, the Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) and Insulin sensitivit...

Obstructive Sleep Apnoea Syndrome

Obstructive Sleep Apnoea Syndrome

Obstructive sleep apnoea and atopy among middle aged chronic obstructive pulmonary disease and bronchial asthma patients.

BACKGROUND Obstructive sleep apnoea syndrome is associated with significant morbidity. A high prevalence of obstructive sleep apnoea (OSA) symptoms has been reported in patients with asthma and chronic obstructive pulmonary disease (COPD). There are limited studies regarding relationship between atopy and OSA. OBJECTIVE To study the risk of obstructive sleep apnoea among middle aged chronic o...